The recent advent of high-throughput approaches has revealed widespread transcription of the human genome, leading to a new appreciation of transcription regulation, especially from noncoding regions.Distinct from most coding and small noncoding RNAs, long noncoding RNAs (lncRNAs) are generally expressed at low levels, are less conserved and lack p
Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin
Abstract Single immune checkpoint blockade in advanced neuroendocrine neoplasms (NENs) shows limited efficacy; dual checkpoint blockade may improve treatment activity.Dune (NCT03095274) is a non-randomized controlled multicohort phase II clinical trial evaluating durvalumab plus tremelimumab activity and safety in advanced NENs.This study included
Effect of casting and rolling process parameters on solidification welding line of magnesium alloy
Process of horizontal twin roll casting magnesium alloy was analyzed by numerical simulation.Taking solidification welding line in cast rolling WOOL RUG area as research object, the characteristic change of solidification welding line caused by casting rolling temperature, casting rolling speed, and roll heat transfer capacity and its influence on
Security-Reliability Tradeoff for Friendly Jammer Assisted User-Pair Selection in the Face of Multiple Eavesdroppers
In this paper, we explore the physical-layer security in a wireless network consisting of multiple user pairs in the face of multiple eavesdroppers, which are deployed Xbox Original by an adversary for tapping the confidential transmissions of the user pairs deliberately.We propose a friendly jammer-assisted user-pair selection (FJaUPS) scheme to i